Proteomics of Follicular Fluid From Women With Polycystic Ovary Syndrome Suggests Molecular Defects in Follicular Development
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چکیده
منابع مشابه
Association between Follicular Fluid Leptin and Serum Insulin Levels in Nonoverweight Women with Polycystic Ovary Syndrome
AIMS We evaluated the links between leptin and visfatin levels and fertilization rates in nonoverweight (NOW) women with PCOS (NOW-PCOS) from Apulia undergoing in vitro fertilization/embryo transfer (IVF). MATERIALS AND METHODOLOGY We recruited 16 NOW women with PCOS (NOW-PCOS) and 10 normally ovulating NOW women (control-NOW). All women underwent IVF. Androgens, 17- β -estradiol (17 β -E2), ...
متن کاملAnti-Mullerian hormone is increased in follicular fluid from unstimulated ovaries in women with polycystic ovary syndrome.
BACKGROUND Anti-Mullerian hormone (AMH) may have a role in disordered folliculogenesis in polycystic ovary syndrome (PCOS). Though there have been several investigations into circulating AMH levels in patients with PCOS, no previous studies have compared AMH concentrations in the follicular fluid of unstimulated ovaries in women with PCOS with that of normally ovulating women. METHODS Follicu...
متن کاملSerum and follicular anti-Mullerian hormone levels in women with polycystic ovary syndrome (PCOS) under metformin
BACKGROUND No data regarding metformin effects on follicular fluid anti-Müllerian hormone (AMH) levels were to date available in literature. The aim of the present study was to evaluate in patients with polycystic ovary syndrome (PCOS) whether metformin administration affects serum and follicular AMH levels, and whether this is related to ovarian response to the treatment. METHODS Twenty youn...
متن کاملP-77: Follicular Fluid Concentrations of Interleukin-6, Interleukin-8, TNF-α and Interleukin 10 in Polycystic Ovarian Syndrome Women
a:4:{s:10:"Background";s:504:"While the etiology of PCOS has continued to remain a mystery, there can be found some evidence in support of the presence of chronic low-grade inflammation in women with this syndrome. One of the most significant manifestations of chronic inflammation is Pro-inflammatory cytokines. Therefore, the aim of this prospective study was to investigate the pattern of proinfla...
متن کاملOvarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome.
BACKGROUND Polycystic ovary syndrome (PCOS) affects 5-10% of reproductive-aged women and is commonly associated with anovulatory infertility. Leukocytes, together with granulosa cells, may contribute to the pathogenesis of PCOS via their ability to secrete an array of cytokines implicated in follicle growth. The aim of this study was to examine leukocyte subtypes in follicular phase ovaries and...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2015
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2014-2086